Westbound lanes of Interstate 12 at O’Neal Lane will be closed from 10 p.m. Saturday until Sunday at 5 a.m., officials said Thursday.

The closure is needed for crews to pour concrete onto the O’Neal Lane overpass, the state Department of Transportation and Development officials said.

Cars and trucks traveling west will have to exit at O’Neal Lane, cross O’Neal and use the O’Neal Lane entrance-ramp to continue on I-12.

Other closures include:

• I-12 westbound will have a left lane closure between the Amite River Bridge and O’Neal Lane from 7 p.m. Saturday until 5 a.m. Sunday.

• I-12 eastbound will have a left lane closure between Millerville Road and O’Neal Lane from 8 p.m. Saturday until 5 a.m. Sunday.

• O’Neal Lane northbound and southbound will be closed under the I-12 overpass from 7 p.m. Saturday until at 9 a.m. Sunday.