Dow Chemical Co. said Tuesday it will lay of 2,500 workers worldwide and shut silicones manufacturing plants in North Carolina and Japan.

It’s unclear whether the job cuts will affect Dow’s more than 6,000 employees and contract workers in Louisiana.

“Workforce consolidations will come from Dow and Dow Corning and will vary by business, function and geography,” spokeswoman Rachelle Schikorra said.

The job cuts amount to roughly 4 percent of Dow’s global workforce. The cuts are part of Dow’s efforts to achieve $500 million in cost savings and boost revenue after taking full control of the Dow Corning Corp.

Dow bought Corning Inc.’s half of Dow Corning for $4.8 billion. Dow and Corning had been partners in the joint venture for more than 70 years.