Copa Airlines is offering nonstop service four times a week between Louis Armstrong New Orleans International Airport and Copa’s Hub of the Americas at Tocumen International Airport in Panama.

New Orleans is the airline’s 11th U.S. destination and will provide access to more than 55 destinations in Central and South America and the Caribbean via Panama.

“This international flight to Panama City, Panama, opens the gateway to the Americas to provide new economic opportunity for the region’s businesses and tourism industry,” said New Orleans Mayor Mitch Landrieu.

Copa flight CM 499 departs New Orleans on Monday, Tuesday, Thursday and Saturday at 7:01 a.m., arriving at Panama City at 10:42 a.m. The return flight, CM 498, departs Panama Monday, Wednesday, Friday and Sunday at 6:33 p.m., arriving in New Orleans at 10:31 p.m.

“We have worked diligently to obtain this flight and build awareness in order to sustain and grow this new international route,” said Iftikhar Ahmad, director of aviation at Louis Armstrong.

Copa is operating a Boeing 737-700 Next-Generation aircraft on the 3½-hour flight, with seating for 12 passengers in business class and 112 in the main cabin.

The airline said the flights are timed for connections to Tegucigalpa and San Pedro Sula, Honduras; San José, Costa Rica; nine destinations in Colombia, including Bogota, Medellin, Cali, Barranquilla and Cartagena; eight destinations in Brazil, including Sao Paulo, Rio de Janeiro, Porto Alegre, Belo Horizonte and Brasilia; Santiago, Chile; Lima, Peru; and Guayaquil and Quito, Ecuador, among other Latin American destinations.

In-transit passengers making connections do not have to go through immigration and customs in Panama, and baggage is checked to the final destination.

Copa’s on-board service includes complimentary meals and beverages, including wines and spirits; a 12-channel audio-visual entertainment system in English, Spanish and Portuguese, with new movies monthly and complimentary headsets. Flight attendants are bilingual.

Established in 1947, Copa Airlines transported more than 11.6 million passengers in 2014.

Copa Airlines and Copa Airlines Colombia, subsidiaries of Copa Holdings, provide passenger and cargo services.

The airline offers service to 71 destinations in 30 countries in North, Central and South America, and the Caribbean. Copa is a member of the Star Alliance global airline network, which offers more than 18,500 daily flights to 1,321 destinations in 193 countries.