Two students dead, others injured after Houston school bus drives off overpass _lowres

An emergency personnel looks inside a school bus after the bus went off a Houston freeway and rolled in southeast Houston on Tuesday, Sept. 15, 2015. The Houston Independent School District says a girl died in Tuesday morning’s accident. Emergency responders say the student was dead at the scene. Officials are trying to determine what caused the crash. A district spokeswoman says it appears the bus went off an overpass. (Cody Duty/Houston Chronicle via AP)

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HOUSTON (AP) — Two students have been killed and three other people are seriously injured after a school bus rolled off a Houston freeway overpass.

A Houston Independent School District statement says a girl died at the scene Tuesday morning, and another student died at a hospital.

The district says two other students and the bus driver were also taken to hospitals with serious injuries.

The bus was bound for Furr High School, which also operates a charter school.

Names of the victims haven't been released.

Officials are investigating the cause of the crash. District spokeswoman Ashley Anthony says the bus apparently drove off an overpass. Guard rails were damaged. The bus rolled and landed on its side.

Houston operates the state's largest public school district with about 215,000 students.