Consider what No. 24 South Carolina is facing Saturday when it plays No. 6 Georgia.

The Gamecocks entered the season with championship hopes, from the SEC East to the national title. A loss Saturday at home, and that’s all gone — on Sept. 13.

Brutal.

South Carolina (1-1, 0-1 SEC) would already have two conference losses and be essentially three games behind Georgia, if you include the tiebreaker the Bulldogs would hold. By Saturday night, a Capital One Bowl bid might be the best the Gamecocks can do.

The annual early-season matchup between South Carolina and Georgia has become one of the SEC’s biggest, a game with national implications, thanks to the Gamecocks’ rise to national power under coach Steve Spurrier.

“We don’t have a whole lot of rivals. We haven’t beaten anybody enough to have rivals,” Spurrier said Wednesday.

That used to be true. South Carolina is coming off three straight 11-win seasons, though Georgia has won the SEC East two of the last four years.

Georgia snapped a three-game losing streak to South Carolina last season with a wild 41-30 victory. Missouri ended up winning the East and will likely have a say in that race again. Maybe Florida and Tennessee, too.

The picks:

MARQUEE MATCHUP

No. 6 Georgia (minus 5½) at No. 24 South Carolina

Never underestimate a desperate team, especially at home ... South Carolina 28-24.

TEST TIME

Tennessee (plus 20½) at No. 4 Oklahoma

Volunteers are improved but also one of the least experienced teams in the country. Last week’s depth chart had 30 players listed as either freshmen or sophomores. Either grow up fast or get taught a painful lesson in Norman ... Oklahoma 45-21.

East Carolina (plus 10½) at No. 17 Virginia Tech

Hokies had a statement victory against Ohio State. Next test is a follow-up against a team that has in recent years given Virginia Tech all it can handle ... Virginia Tech 28-20.

CONFERENCE CALLS

No. 16 Arizona State (minus 15½) at Colorado

Sun Devils have never lost to Buffaloes in five meetings ... Arizona State 48-31.

No. 21 Louisville (minus 6½) at Virginia

ACC newbie Cardinals go on road for first time in conference ... Louisville 24-20.

WORTH A LOOK

No. 9 Southern California (minus 17) at Boston College

USC star DT Leonard Williams has been nursing a sore ankle. Didn’t stop him from eating up Stanford last week. Eagles beware ... USC 28-13.

BEST BET

No. 12 UCLA (minus 8) vs. Texas at Arlington, Texas

Bruins have been underwhelming. They’re also 2-0, so all is not horrible. Horrible was the Longhorns last week. ... UCLA 28-17.

UPSET SPECIAL

West Virginia (plus 3) at Maryland

Terps snapped seven-game losing streak to Mountaineers last year with 37-0 victory. ... West Virginia 31-24.

COULD GET UGLY

No. 8 Baylor (minus 35) at Buffalo, Friday

Bulls have allowed 75 points in two games — against Duquesne and Army. Maybe hope for snow? ... Baylor 66-21.

Rice (plus 32) at No. 7 Texas A&M

Aggies go for first 3-0 start under coach Kevin Sumlin ... Texas A&M 52-24.

Louisiana-Monroe (plus 31) at No. 10 LSU

Tigers have not allowed a point in opponents’ last 19 possessions ... LSU 48-14.

No. 11 Notre Dame (minus 28) vs. Purdue at Indianapolis

Shamrock Series time for Notre Dame, so prepare for some uniform weirdness ... Notre Dame 41-10.

UL-Lafayette (plus 27) at No. 14 Ole Miss

Rebels have allowed 16 points in two games ... Ole Miss 35-14.

Army (plus 28) at No. 15 Stanford

Good opportunity for Cardinal to fix red-zone issues ... Stanford 48-17.

Kent State (plus 32) at No. 22 Ohio State

No better way for Buckeyes to get better than with in-state opponent. They’ve won 38 straight against Ohio schools ... Ohio State 38-7.