While it seems doubtful that safety Jairus Byrd and C.J. Spiller will play this week against the Arizona Cardinals, things took another step toward that reality on Wednesday.

Both players sat out of Wednesday’s practice due to knee injuries. Linebacker Dannell Ellerbe (toe), running back Tim Hightower (knee), cornerback Keenan Lewis (hip), and linebacker Davis Tull (shoulder) also did not participate.

Cornerback Brandon Browner and running back Khiry Robinson practiced. Both players were recently fighting injuries.

Lewis, Spiller, Tull, Ellerbe, and Hightower were spotted at practice during the portion that is open to the media. Byrd was not in the practice facility during that period.