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The New Orleans Saints (1-1) enter their third consecutive NFC South game to open the 2022 season, and this one couldn’t be much more important in facing the 0-2 Panthers. Going just short of calling it a “must win,” Jim Derry and Spencer “The Guru” Urquhart dive into their thoughts on the prospects of what might happen in Charlotte on Sunday.

This is just the open of Thursday’s “Bayou Bets” show, which is Louisiana's twice-weekly sports betting show powered by Caesars Sportsbook, official odds partner of Bet.NOLA.com.

We also talk about LSU (2-1) hosting New Mexico (2-1) at Tiger Stadium on Saturday at 6:30 p.m. Also, Tulane, which is fresh off their big win at Kansas State is a 13-point favorite at home against Southern Miss. Do we smell letdown for the Green Wave?

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The Bayou Bets crew also discussed their top picks for the rest of the weekend, with Spencer "The Guru" Urquhart saying his best bet was the desperate Cincinnati Bengals laying 5 to the New York Jets, Zach Ewing, who was out sick, sent in his picks and took the “other” Cincinnati, as in the Bearcats over Indiana by 16.

Jim Derry, who hosted the show for Zach on Thursday, likes the Minnesota Vikings to bounce back at home to beat the Detroit Lions by more than 6.

To watch the full episode on demand, visit Bet.NOLA.com or the Bayou Bets YouTube page. The show airs live at 4 p.m. every Monday and Thursday.

Contact Jim Derry at jderry@theadvocate.com.